HFNC Machine(OXYGEN THERAPY) can warm and humidify gas, which can decrease airway inflammation, maintain mucociliary function, improve mucous clearance and reduce the caloric expenditure in acute respiratory failure. This therapy is an oxygen supply system capable of delivering up to 100% humidified and heated oxygen at a flow rate. HFNC Machine(OXYGEN THERAPY)has occurred despite relatively little scientific knowledge into the mechanisms of action and clinical efficacy. This minimizes entrainment of room air and dilution of delivered oxygen by providing oxygen at flows high enough to match or exceed a patients inspiratory drive.